Clinical Evidence

ATTUNE Knee Evidence Summaries

ATTUNE Knee System Evidence Brochure
Improving the Value of Primary Total Knee Arthroplasty: The ATTUNE Knee System
ATTUNE Knee Patellofemoral Overview
ATTUNE Knee Evidence Visual Aid

Patient Reported Outcome Measures

Early Outcomes with a New Primary TKA System vs. Contemporary TKA Interim Results of Two Worldwide Multi-Center Prospective Studies
Improving the Value of Primary Total Knee Arthroplasty: The ATTUNE Knee System

Joint Registry Data and Implant Survivorship Studies

Michigan Arthroplasty Registry Collaborative Quality Initiative (MARCQI)
Improving the Value of Primary Total Knee Arthroplasty: The ATTUNE Knee System
NJR Implant Summary Report for ATTUNE Knee CR and PS, February 2019 Report
Kaiser Permanente Total Joint Registry
ATTUNE Knee Improved Survivorship Clinical Outcomes P.F.C. SIGMA Knee
NJR Implant Summary Report Presentation
OANJRR Automated Industry Report (AIRS) ATTUNE Knee CR
AOANJRR Automated Industry Report (AIRS) ATTUNE Knee PS
AIRS ATTUNE Knee CR/PS Report Presentation

Health Economics Data

Hospital Length of Stay and Discharge Disposition after Primary Total Knee Arthroplasty
Improving the Value of Primary Total Knee Arthroplasty: The ATTUNE Knee System
April 2017 Orthopedics Today ATTUNE Knee Supplement
The Impact of Implant Design on Hospital Length of Stay and Discharge Destination

Early User Studies

ATTUNE Knee Improved Survivorship Clinical Outcomes P.F.C. SIGMA Knee

An Early Outcome Study of the ATTUNE Knee System vs. the SIGMA® CR150 Knee System

 

 

References

1. Indelli P.F., Pipino G., Johnson P., Graceffa A., Marcucci M. Posterior-stabilized total knee arthroplasty: a matched pair analysis of a classic and its evolutional design. Arthroplasty Today 2016; 206,2(4):193-1986. Implants tested: P.F.C. SIGMA and ATTUNE Knee.

2. Ranawat C.S., White P.B., West S., Ranawat A.S., Clinical and Radiographic Results of Attune and PFC Sigma Knee Designs at 2-Year Follow-Up: A Prospective Matched-Pair Analysis. J Arthroplasty 2017;32:431-6. Implants tested: P.F.C. SIGMA and ATTUNE Knee.

3. Martin J.R., Jennings J.M., Watters T.S., Levy D.L., McNabb D.C., Dennis D.A. Femoral Implant Design Modification Decreases the Incidence of Patellar Crepitus in Total Knee Arthroplasty. J Arthroplasty. 2017 Apr;32(4):1310-1313. Implants tested: P.F.C. SIGMA and ATTUNE Knee.

4.Toomey, S.D., Daccach, J., Shah, J., Himden, S., Lesko, J., Hamilton W.G.: Comparative Incidence of Patellofemoral Complications Between Two Total Knee Arthroplasty Systems in a Multi-Center, Prospective Clinical Study. J Arthroplasty, available online, April 2017. Implants tested: P.F.C. SIGMA (DePuy)

5. Hamilton WG, Brenkel I, Clatworthy M, et al. Comparison of an Existing and New Total Knee Arthroplasty Implant System from the Same Manufacturer. A Prospective, Multicenter Study. Closed Meeting of the Knee Society. 2018. SRR 10850.

6. Clatworthy, M. (2015). An Early Outcome Study of the ATTUNE Knee System vs. the SIGMA® CR150 Knee System. DePuy Synthes Companies White Paper. DSUS/JRC/0814/0418(1). In an IRB approved early outcomes study, physiotherapists collected data on 40 patients implanted with ATTUNE® Knees and 40 patients with SIGMA®CR150 knees. The results demonstrated that patients implanted with the ATTUNE Knee had statistically significant improvements in some early outcomes, other outcomes demonstrated a trend favoring the ATTUNE Knee, and some outcomes were equivalent.

7. Etter, K., Lerner, J., de Moor, C, Yoo, A., Kalsekar, I. (2016). PMD10-Comparative Effectiveness of ATTUNE® Versus TriathlonTM Total Knee Systems: Real-World Length of Stay and Discharge Status.”Value in Health 19(3): A298. Premier PerspectiveTM Database analysis including 38 hospitals, representing 1,178 primary, unilateral TKAs with the ATTUNE Knee and 5,707 primary, unilateral TKAs with TriathlonTM. The analysis found that the patients implanted with the ATTUNE Knee had statistically shorter length of stay and were more frequently discharged home vs. a skilled nursing facility compared to the TKAs with TriathlonTM.

 

The ATTUNE Knee System is backed by a comprehensive evidence generation program that encompasses clinical and patient reported outcomes (PROMS) as well as value based healthcare studies.

The early clinical results of the ATTUNE Knee are promising and include data from national registries, company initiated, independent studies, and investigator initiated studies, as noted in the articles and papers.

 

All medical devices have associated risks. Please refer to the instructions for use and other labeling for a complete list of indications, contraindications, precautions and warnings.

For further information on DePuy Synthes products, please contact your local DePuy Synthes Representative .

 

089946-180410